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Modes of Action & Resistance Management

Resistance is arithmetic: kill 99% with one site of action and you've just bred the 1%. Here's how to keep chemistry working on your farm.

๐Ÿ“– 7 min read๐ŸŽ“ Application Science๐Ÿ“ฑ Mobile-friendly
Look for the group number on the label โ€” HRAC/WSSA for herbicides, FRAC for fungicides, IRAC for insecticides. Same number = same site of action = no resistance benefit from "switching products."

Rotate is good; overlap is better

Old advice was "rotate chemistry each year." Current weed-science consensus: use multiple effective sites of action in the same pass. A weed surviving Group 15 must also survive Group 5 in the tank โ€” the odds of both mutations collapse. Rotation across seasons still matters, but the tank mix does the heavy lifting.

"Effective" is the operative word: adding a group your weeds are already resistant to isn't a second site of action, it's expensive water.

The five non-chemical multipliers

Fungicides and insecticides deserve the same discipline

FRAC 11 (strobilurin) resistance in frogeye leaf spot and IRAC 3 (pyrethroid) failures are real in row crops. For fungicides, prefer pre-mixes with two effective FRAC groups and hold single-site products for the pass that needs them. For insects, scout to threshold rather than spraying insurance passes โ€” every unnecessary application is selection pressure.

A one-page plan you can actually follow

  1. List your top 3 problem pests/weeds per field.
  2. Write the group numbers you used last season (from records).
  3. Plan this season with โ‰ฅ2 effective groups per target, changing at least one from last year.
  4. Record actual groups applied in your application log โ€” that's the data next year's plan needs.

Group classifications per HRAC/WSSA, FRAC, IRAC. Mixing mechanics: adjuvants & tank mixing.

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